Clocortolone pivalate
Clocortolone Pivalate, Cloderm (clocortolone pivalate) is a small molecule pharmaceutical. Clocortolone pivalate was first approved as Cloderm on 1982-01-01. It is used to treat facial dermatoses, foot dermatoses, hand dermatoses, inflammation, and leg dermatoses amongst others in the USA.
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Clocortolone pivalate, Cloderm
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| clocortolone pivalate | ANDA | 2021-12-21 |
| cloderm | New Drug Application | 2022-11-02 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| inflammation | MP_0001845 | D007249 | — |
| facial dermatoses | — | D005148 | — |
| foot dermatoses | — | D005533 | — |
| hand dermatoses | — | D006229 | — |
| scalp dermatoses | — | D012536 | — |
| leg dermatoses | — | D007868 | — |
Agency Specific
FDA
EMA
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Clinical
Clinical Trials
2 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Psoriasis | D011565 | EFO_0000676 | L40 | — | — | — | 1 | — | 1 |
Indications Phases 3
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Indications Phases 2
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Therapeutic equivalency | D013810 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Clocortolone pivalate |
| INN | — |
| Description | Clocortolone pivalate is the 21-O-pivalate ester of clocortolone. It is used for the relief of inflammatory and pruritic (itching) skin disorders. It has a role as an anti-inflammatory drug and an antipruritic drug. It is a glucocorticoid, an 11beta-hydroxy steroid, a pivalate ester, a 20-oxo steroid, a fluorinated steroid, a 3-oxo-Delta(1),Delta(4)-steroid and a chlorinated steroid. It is functionally related to a clocortolone. |
| Classification | Small molecule |
| Drug class | cortisone derivatives; steroids (not prednisolone derivatives) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@H]1C(=O)COC(=O)C(C)(C)C |
Identifiers
| PDB | — |
| CAS-ID | 34097-16-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1200975 |
| ChEBI ID | 59583 |
| PubChem CID | 5282493 |
| DrugBank | DB00838 |
| UNII ID | — |
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Cloderm – Novan
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Safety
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35 adverse events reported
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